Lecturer:
Jeff Gladd, MD, CHAIRMAN Susan Blum, MD Tom O'Bryan, DC Shayma Kazmi, MD, RPh Mark Tager, MD James Maskell Derrick DeSilva, Jr, MD Jacques Simon, Esq Sarath Malepati, MD Ron Hoffman, MD Joel Evans, MD Anita Teresa Boeninger, RYT Melissa Crispell Joseph Hickey, MD Mette Dyhrberg Thomas Blomseth Christiansen Lillie Rosenthal, DO Mark Menolascino, MD Georgia Tetlow, MD Aimon Kopera, MD & Peter Evans, PhD
Lecturer:
Erik Goldman Jeff Gladd, MD Shilpa Saxena, MD Michael Gaeta, Lac Chad Larson, NMD, DC Steven Masley, MD David Perlmutter, MD Marcela Dominguez, MD Erin Martin, DO Richard Jaffe, Esq. Deanna Minich, PhD Harry Massey Miriam Zacharias James Maskell John La Puma, MD Tina Beaudoin, ND Mette Dyhrberg & Thomas Blomseth Christiansen
Targeted Nutritional Interventions for Improved Cognitive, Cardiovascular, Gastrointestinal & Musculoskeletal Health
A growing body of basic and clinical research shows that targeted nutritional interventions with specific amino acids and vitamins can markedly improve metabolic function at the cellular level in many tissues. This, in turn, can translate into meaningful functional improvements across multiple organ systems, over and above what can be achieved through dietary changes and exercise alone. Free for Registered Users.
This 4-part learning activity explores the science behind four such nutraceutical ingredients:
Cognizin: Also known as cytidine diphosphate choline or “citicoline,” Cognizin increases production of neurotransmitters like acetylcholine, dopamine and noradrenaline; maintains the integrity of neuronal membranes; and increases mitochondrial energy production in the frontal cortex.
Sustamine: a fixed combination (dipeptide) of the amino acids L-alanine and L-glutamine which, taken as the dipeptide, increases production and inhibits degradation of skeletal muscle protein, enhances the integrity of intestinal mucosa, balances immune system responses; and increases electrolyte and fluid transport across the intestinal lining. The individual amino acids do not have the same benefits.
Pantesin: a highly-absorbable form of Vitamin B5, which has been shown to improve lipid profiles, producing favorable shifts in LDL, HDL and total cholesterol.
Setria: an ultra-pure and stable form of reduced glutathione, one of the body’s key defenses against oxidative stress and the damaging effects of exogenous toxins.
Join dietitian Karen Todd, RD, and pharmacist Danielle Citrolo, PharmD, as they discuss these innovative nutraceutical ingredients, their physiological effects, and their potential role in optimizing neurocognitive, cardiovascular, gastrointestinal and musculoskeletal health.
This Learning Center is supported by an unrestricted educational grant from Kyowa Hakko USA
Kyowa
Course: Targeted Nutritional Interventions for Improved Cognitive, Cardiovascular, Gastrointestinal & Musculoskeletal Health
Faculty
Lecture 1: Cognizin: A Novel Ingredient to Support Healthy Cognitive Function
Lecture 2: Sustamine: A New Approach for Rehydration & Improved Electrolyte Balance
Lecture 3: Pantesin: A Novel Form of Pantethine (Vitamin B5) to Support Heart Health
Lecture 4: Setria: A Unique Form of Reduced Glutathione for Reducing Oxidative Stress
Course: Targeted Nutritional Interventions for Improved Cognitive, Cardiovascular, Gastrointestinal & Musculoskeletal Health
Faculty and Disclosures
Danielle Citrolo, PharmD, is a registered pharmacist currently serving as Manager of Technical Services for Kyowa Hakko USA. Prior to joining Kyowa, Dr. Citrolo was the Clinical Coordinator at The Hospital for Special Surgery in New York City, and provided support and guidance to pharmacy staff on policy and procedure. Dr. Citrolo earned her Doctor of Pharmacy degree from Albany College of Pharmacy in New York. She is licensed by the New York State Board of Pharmacy.
Karen E. Todd, RD, is a Registered Dietitian, Certified Strength and Conditioning Specialist and Health & Fitness Specialist with more than 20 years experience in exercise performance and nutritional product development and education. Currently, she is the Director of Marketing for Kyowa Hakko U.S.A and Principal of Optimal Performance & Nutrition where she advises athletes on optimal diets and exercise routines specific to their sport. She holds Bachelor's of Science degrees in Scientific Nutrition and Food Science Technology from Texas A&M University and an MBA from the Huizenga School of Business at Nova Southeastern University.
Lecture 1: Cognizin: A Novel Ingredient to Support Healthy Cognitive Function
Cognizin, a supplemental form of citicoline, is a precursor to several important brain phospholipids, including phosphatidylcholine, which makes up 30% of brain tissue. In this interview, Karen Todd & Danielle Citrolo review the basic and clinical research on supplementation with Cognizin, including human studies showing enhanced neuronal ATP production, reduction of oxidative damage, and improved inter-neuronal communication, leading to improved focus and attention.
Lecture 2: Sustamine: A New Approach for Rehydration & Improved Electrolyte Balance
Sustamine, is a dipeptide consisting of the amino acids L-alanine and L-glutamine, linked by a peptide bond. L-alanine is a good source of energy, while L-glutamine is important in building muscle. Taken in the dipeptide form, the combination is highly absorbed owing to a very specific transporter in the gut. In this segment, Karen Todd & Danielle Citrolo review clinical studies showing that supplementation with Sustamine increases hydration and improves endurance in high-performance athletes.
Lecture 3: Pantesin: A Novel Form of Pantethine (Vitamin B5) to Support Heart Health
Pantesin is a derivative of B5, with unique chemical and physiological properties. It maintains cholesterol within normal limits, and improves blood flow. It has been the subject of many studies that show clinically meaningful effects on multiple lipid measures. In this segment, Karen Todd & Danielle Citrolo outline clinical data suggesting that Pantesin is a safe and effective alternative for maintaining heart health for people who would not be candidates for more intensive interventions.
Lecture 4: Setria: A Unique Form of Reduced Glutathione for Reducing Oxidative Stress
Glutathione is a tripeptide antioxidant that has garnered considerable research attention in recent years. A powerful antioxidant, it also plays a role in hepatic detoxification pathways, and in immune system function. Endogenous glutathione production declines with aging, serious illness, intense stress, exposure to toxins, and excessive exercise. Karen Todd & Danielle Citrolo review the clinical data supporting use of Setria to raise circulating levels of Glutathione.
Danielle Citrolo, PharmD, is a registered pharmacist currently serving as Manager of Technical Services for Kyowa Hakko USA. Prior to joining Kyowa, Dr. Citrolo was the Clinical Coordinator at The Hospital for Special Surgery in New York City, and provided support and guidance to pharmacy staff on policy and procedure. Dr. Citrolo earned her Doctor of Pharmacy degree from Albany College of Pharmacy in New York. She is licensed by the New York State Board of Pharmacy.
Cognizin, a supplemental form of citicoline, is a precursor to several important brain phospholipids, including phosphatidylcholine, which makes up 30% of brain tissue. In this interview, Karen Todd & Danielle Citrolo review the basic and clinical research on supplementation with Cognizin, including human studies showing enhanced neuronal ATP production, reduction of oxidative damage, and improved inter-neuronal communication, leading to improved focus and attention.
Sustamine, is a dipeptide consisting of the amino acids L-alanine and L-glutamine, linked by a peptide bond. L-alanine is a good source of energy, while L-glutamine is important in building muscle. Taken in the dipeptide form, the combination is highly absorbed owing to a very specific transporter in the gut. In this segment, Karen Todd & Danielle Citrolo review clinical studies showing that supplementation with Sustamine increases hydration and improves endurance in high-performance athletes.
Pantesin is a derivative of B5, with unique chemical and physiological properties. It maintains cholesterol within normal limits, and improves blood flow. It has been the subject of many studies that show clinically meaningful effects on multiple lipid measures. In this segment, Karen Todd & Danielle Citrolo outline clinical data suggesting that Pantesin is a safe and effective alternative for maintaining heart health for people who would not be candidates for more intensive interventions.
Glutathione is a tripeptide antioxidant that has garnered considerable research attention in recent years. A powerful antioxidant, it also plays a role in hepatic detoxification pathways, and in immune system function. Endogenous glutathione production declines with aging, serious illness, intense stress, exposure to toxins, and excessive exercise. Karen Todd & Danielle Citrolo review the clinical data supporting use of Setria to raise circulating levels of Glutathione.